Through games of Feb. 26, 2006:
| # | Team | W-L | Pts. | Last Week |
| 1 | Southern Maine (19) | 27-1 | 618 | 1 |
| 2 | Scranton (2) | 26-1 | 598 | 2 |
| 3 | Washington U. (2) | 23-2 | 539 | 3 |
| 4 | DePauw (2) | 27-1 | 535 | 5 |
| 5 | Bowdoin | 24-2 | 530 | 6 |
| 6 | Hope | 27-1 | 514 | 7 |
| 7 | Randolph-Macon | 25-2 | 450 | 8 |
| 8 | Mary Washington | 27-1 | 430 | 4 |
| 9 | Messiah | 25-2 | 428 | 9 |
| 10 | Capital | 25-3 | 359 | 11 |
| 11 | McMurry | 26-2 | 345 | 12 |
| 12 | Baldwin-Wallace | 24-4 | 327 | 10 |
| 13 | Brandeis | 19-4 | 317 | 13 |
| 14 | Wheaton (Ill.) | 23-4 | 292 | 16 |
| 15 | Muhlenberg | 25-2 | 285 | 15 |
| 16 | Pacific Lutheran | 22-3 | 255 | 17 |
| 17 | Calvin | 23-4 | 230 | 14 |
| 18 | Simpson | 23-4 | 195 | 19 |
| 19 | Maryville (Mo.) | 23-4 | 126 | 23 |
| 20 | Howard Payne | 23-4 | 124 | 18 |
| 21 | UW-Stout | 20-7 | 104 | — |
| 22 | Puget Sound | 22-5 | 88 | 21 |
| 23 | Williams | 21-5 | 72 | 20 |
| 24 | Bates | 19-8 | 69 | 25 |
| 25 | Medaille | 25-1 | 67 | — |
Dropped out: No. 22 Hardin-Simmons; No. 24 Moravian.
Others receiving votes: Salem State 65, Moravian 45, Washington and Jefferson 26, Hardin-Simmons 21, Carroll 20, Mount St. Mary 17, Rochester 12, Cortland State 5, Richard Stockton 5, St. Benedict 4, Trinity (Texas) 3, Gwynedd-Mercy 1, Maine-Farmington 1, Oglethorpe 1.
The D3hoops.com Top 25 is voted on by a panel of 25 coaches, Sports Information Directors and media members from across the country, and is published weekly.