Through games of Feb. 19, 2006:
| # | Team | W-L | Pts. | Last Week |
| 1 | Lawrence (22) | 22-0 | 622 | 2 |
| 2 | Hope (1) | 23-2 | 571 | 5 |
| 3 | Wooster (2) | 23-2 | 569 | 1 |
| 4 | York (Pa.) | 23-2 | 536 | 6 |
| 5 | Amherst | 23-2 | 515 | 7 |
| 6 | Wittenberg | 22-3 | 478 | 4 |
| 7 | Baldwin-Wallace | 21-4 | 419 | 3 |
| 8 | Virginia Wesleyan | 24-3 | 391 | 12 |
| 9 | Augustana | 21-4 | 374 | 9 |
| 10 | Mississippi College | 24-1 | 360 | 11 |
| 11 | Albion | 19-5 | 356 | 8 |
| 12 | Illinois Wesleyan | 19-5 | 344 | 10 |
| 13 | Calvin | 20-5 | 315 | 19 |
| 14 | UW-Stout | 19-5 | 298 | 13 |
| 15 | Carroll | 20-3 | 276 | 14 |
| 16 | St. John Fisher | 22-3 | 263 | 16 |
| 17 | Puget Sound | 20-4 | 260 | 17 |
| 18 | Lincoln | 20-4 | 217 | 18 |
| 19 | North Central | 20-5 | 202 | 21 |
| 20 | UW-Whitewater | 19-5 | 164 | 24 |
| 21 | Transylvania | 21-4 | 134 | 23 |
| 22 | Ohio Northern | 19-5 | 63 | — |
| 23 | Worcester Polytech | 20-3 | 59 | — |
| 24 | Carnegie Mellon | 19-5 | 55 | 20 |
| 25 | Randolph-Macon | 22-5 | 47 | — |
Dropped out: No. 15 Occidental; 22 Wartburg; No. 25 Elmhurst.
Others receiving votes: Occidental 43, Wartburg 39, Elmhurst 37, Whitworth 28, Carleton 20, St. Thomas 16, Trinity (Conn.) 12, Cortland State 12, Tufts 9, Wilmington 4, Ursinus 4, Washington U. 3, Trinity (Texas) 3, UW-La Crosse 2, New Jersey City 2, Claremont-Mudd-Scripps 1, UW-Stevens Point 1, UW-Oshkosh 1.
The D3hoops.com Top 25 is voted on by a panel of 25 coaches, Sports Information Directors and media members from across the country, and is published weekly.