Coast Guard jumped out to an 11-2 lead in the first eight minutes of the game and took a 22-15 lead into halftime.
Coast Guard led 27-19 with 14:53 left in the second half when the Bears used a 16-0 run to put the game away, taking a 43-19 lead with 7:57 left in the game.
Holly Bucheit led Coast Guard (6-3, 2-0) with seven rebounds while Kira Peterson had a game-high seven assists. DeCarol Davis was the Bears' second leading scorer on the day with eight points.
Karen Kinnaman led MIT (3-5, 0-1) with nine points and a game-high 14 rebounds.