After falling behind by eight early in the contest, Hobart closed to within one, 13-12, on a layup by senior guard Adam Frederic (Holy Cross/Flushing, N.Y.) at the 12:19 mark.
From there, the Yellowjackets went on a 19-2 run to seize control of the game. Junior guard Tim Brackney (Archbishop Spalding/Columbia, Md.) keyed the surge with five of his 12 points on the night.
Rochester, which shot 45.5 percent from the floor in the first half while holding the Statesmen to just 25.9 percent, led 36-18 at halftime.
After the break, both teams subbed liberally playing a much more even game, but Hobart never got closer than 15 down.
Sophomore center Jon Onyiriuka (Corning West/Painted Post, N.Y.) led the Yellowjackets with 15 points, six rebounds, and three blocked shots.
Junior guard Mike Manning (Center Moriches/Mastic, N.Y.) was the only Statesman in double digits, recording 10 points.
Hobart plays its final game before the holiday break on Dec. 17, at Division I Colgate. Tipoff is scheduled for 2:30 p.m.
UNIVERSITY OF ROCHESTER 64, HOBART COLLEGE 45 UNIVERSITY OF ROCHESTER (6-2) Jon Onyiriuka 6-10 3-3 15; Tim Brackney 5-10 0-0 12; Jeff Juron 2-4 0-0 6; Dan Milbrand 3-3 0-0 6; Dmitry Razin 1-2 3-4 5; Mike Goia 2-7 0-0 4; Uche Ndubizu 2-4 0-0 4; Max Kaplan 1-4 0-0 3; Joe Canty 1-5 0-0 3; William Thorne 1-3 0-0 2; Eric Snider 1-2 0-0 2; Robert Dominiak 1-4 0-0 2; Brian Baudinet 0-3 0-0 0; Michael Chmielowiec 0-5 0-0 0. Totals 26-66 6-7 64. HOBART COLLEGE (2-4) Mike Manning 4-9 0-0 10; Colby Feane 3-14 2-2 9; Dan O'Grady 2-3 2-2 6; Adam Frederic 2-4 1-3 5; Rob Genovese 1-6 1-2 4; Doug Murphy 2-3 0-0 4; Mike Mastro 1-1 1-2 3; Cory Keeling 1-3 0-0 2; John Grazioli 1-4 0-0 2; Assim Cunningham 0-3 0-0 0; Joe Virgilio 0-3 0-0 0; Kevin Riley 0-3 0-0 0; Tim Apuzzo 0-3 0-0 0. Totals 17-59 7-11 45. Halftime-Rochester 36, Hobart 18. 3-point goals-Rochester 6-23 (Brackney 2-7; Juron 2-2; Canty 1-3; Kaplan 1-3; Dominiak 0-3; Baudinet 0-1; Chmielowiec 0-1; Goia 0-3), Hobart 4-16 (Manning 2-4; Genovese 1-3; Feane 1-6; Keeling 0-1; Virgilio 0-1; Frederic 0-1). Fouled out-None. Rebounds-Rochester 42 (Snider 7), Hobart 37 (Genovese 5; Riley 5). Assists-Rochester 14 (Juron 3), Hobart 12 (Frederic 2; Feane 2; Riley 2; Genovese 2; Apuzzo 2). Total fouls-Rochester 11, Hobart 10. A-150