Senior guard Brett Sjoberg scored a career-high 14 points to pace Lawrence (3-0), ranked fourth by D3hoops.com. Fourteen players scored for Lawrence, which ran its winning streak at Alexander Gym to 18 games.
The Vikings hit 31 of 51 shots from the floor (60.8 percent), including 10 of 18 (55.6 percent) from beyond the 3-point arc.
Kevin Christensen scored 12 points on 4 of 18 shooting from the floor to lead Wisconsin Lutheran (1-5).
The Vikings pulled away early, building a 16-3 lead on Sjoberg's 3-pointer with 13:32 left in the first half. Lawrence's biggest lead in the first half was 46-16 on Ben Rosenblatt's 3-pointer with 2:14 left.
Lawrence led 50-24 at the half, and Wisconsin Lutheran never got closer than 23 points in the second half. Lawrence built its lead to as many as 41 points in the second half.
Lawrence is back in action Saturday when it travels to Ripon College to open the Midwest Conference season.