The Quakers and Yellow Jackets battled back and forth for the first half until the visitors opened an 11-0 run, taking a 14-point lead that was shrunk to 12 by halftime.
The Yellow Jackets scored the first five points of the second half, increasing their lead to 17 before the hosts went on a 16-0 run, cutting the deficit to one with 14:41 to play in the game. The Quakers took their first lead of the period with 6:22 to play, and increased the lead to as many as five with 4:12 to play in the contest. Defiance cut it to one on two occasions, but were not able to overcome the Green and White.
David Guy led the Quakers with 19 points while Eric Stirling and Josh Rohrbacher had 14 and 12 while Zach Broermann and Deon Short each had 11 points. Short pulled down a team-high six rebounds while dishing out a trio of assists to pace the squad.
Defiance was led by Phil Blasko who had 17 points while Matt Voland had 13 points, Ryan Farmer 11 and Mike Lentz and Brett Hammons each scored 10.
With the win, the Quakers improve to 1-0 on the year while Defiance falls to 0-1.
The Quakers next take the court tomorrow when they play host to Anderson University, who was defeated 86-76 by Thomas More College in the early game of the afternoon.