Micheal Morak led CM with 19 points, seven steals, and four rebounds while Andre Little added 18 points and one rebound.
Corey Brown and Josh Kendrick each had 12 points for the Cougars.
Nate Francis was eight for 11 in three-point range to lead the team with 27 points and four rebounds.
David Stallard had 18 points for the Defenders while Jon Konzelman added 11 points.
The Cougars, 0-1, will face Briarcliffe in the consolation game, Saturday at 6:00.
Baptist Bible will face Marywood in the Laurel Line Championship game at Misericordia, 8:00.